Opioid antagonist nalmefene
1961, Dr. Jack Fishman and Dr. Mozes Lewenstein applied for one of the first patents for naloxone. 1971, the Food and Drug Administration (FDA) approved using naloxone to treat overdoses. 1995, the FDA has granted OxyContin drugmaker Purdue Pharma, fast track designation for opioid overdose antidote Revex nalmefene hydrochloride (HCl) injection. However, the besieged firm [...]